Linkage of essential hypertension to the angiotensinogen locus in Mexican Americans.

doi:10.1161/01.hyp.30.3.326

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Article

Linkage of essential hypertension to the angiotensinogen locus in Mexican Americans.

Hypertension (Dallas, Tex. : 1979) - 1 Sept 1997

Atwood L D, Kammerer C M, Samollow P B, Hixson J E, Shade R E, MacCluer J W

Abstract excerpt

Essential hypertension has been linked to a highly polymorphic marker at the angiotensinogen locus, and association with a polymorphism in this locus has been found in some populations. We tested the hypothesis that these same polymorphic markers are linked to essential hypertension in Mexican Americans. The data comprised all the affected relative pairs in 46 extended families chosen at random from a low-income...

Topics

Adult
Angiotensinogen
Body Mass Index
Chromosome Mapping
Dinucleotide Repeats
Female
Genetic Linkage
Genetic Variation
Genotype
Humans
Hypertension
Male
Mexican Americans
Middle Aged
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 9314412
DOI: 10.1161/01.hyp.30.3.326

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