Article
Angiotensinogen gene polymorphisms M235T/T174M: no excess transmission to hypertensive Chinese.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 1999
Niu T, Yang J, Wang B, Chen W, Wang Z, Laird N, Wei E, Fang Z, Lindpaintner K, Rogus J J, Xu X
Abstract excerpt
The gene encoding angiotensinogen (AGT) has been widely studied as a candidate gene for hypertension. Most studies to date have relied on case-control analysis to test for an excess of AGT variants among hypertensive cases compared with normotensive controls. However, with this design, nothing guarantees that a positive finding is due to actual allelic association as opposed to an inappropriate control...
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