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Article

Roles of DT diaphorase in the genotoxicity of nitroaromatic compounds in human and fish cell lines.

Journal of toxicology and environmental health - 10 Oct 1997

Hasspieler B M, Haffner G D, Adeli K

Abstract excerpt

The genotoxicity of nitroaromatic compounds was examined in two cultured cell lines, namely, a human hepatoma cell line, HepG2, and a brown bullhead fibroblast cell line, BB. Furthermore, the role of the quinone-reducing enzyme DT diaphorase [NAD(P)H:(quinone acceptor) oxidoreductase] was examined with respect to its influence on the genotoxic effects of model nitroaromatic pollutants. The nitroreductive...

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Identifiers

PMID: 9310146
DOI: 10.1080/00984109708984057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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