Article
Activated protein C resistance and anticardiolipin antibodies in patients with venous leg ulcers.
Journal of the American Academy of Dermatology - 1 Sept 1997
Grossman D, Heald P W, Wang C, Rinder H M
Abstract excerpt
BACKGROUND: Hypercoagulable states, which include the presence of anticardiolipin antibodies (ACAs), have been associated with skin ulceration. Resistance to activated protein C (APC), resulting from the factor V Leiden mutation, is a common risk factor for venous thrombosis. Its prevalence among patients with venous leg ulcers is not known. OBJECTIVE: Our purpose was to determine the prevalence of factor V...
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