Article
A prospective coagulation study including resistance to activated protein C and mutations in factors V and II in venous leg ulcers.
The British journal of dermatology - 1 Aug 1999
Ribeaudeau F, Senet P, Cayuela J M, Fund X, Paul C, Robert C, Scrobohaci M L, Dubertret L
Abstract excerpt
Hypercoagulable states have been reported to be associated with venous leg ulcers. In an attempt to investigate the prevalence of hypercoagulable states in patients with venous leg ulcers, we performed a prospective case-control study for the presence of coagulation defects in such patients, including resistance to activated protein C (APC), factor V Leiden mutation and a newly described mutation in factor II....
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