Article
TAP1 and TAP2 genes in nickel allergy.
International archives of allergy and immunology - 1 Sept 1997
Silvennoinen-Kassinen S, Ikäheimo I, Tiilikainen A
Abstract excerpt
The study was undertaken to see whether TAP1 and TAP2 (transporter associated with antigen processing) genes are involved in susceptibility to nickel allergy. The products of these genes are important in antigen transport and processing, making them candidates for disease susceptibility. Fifty-five nickel-sensitive and 54 non-sensitive subjects were TAP1- and TAP2-typed by amplification refractory mutation system...
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