Article
Decreased tumour necrosis factor-beta production in TNFB*2 homozygote: an important predisposing factor of lupus nephritis in Koreans.
Lupus - 1 Jan 1997
Lee S H, Park S H, Min J K, Kim S I, Yoo W H, Hong Y S, Park J H, Cho C S, Kim T G, Han H, Kim H Y
Abstract excerpt
Low TNF production and its association with TNF gene restriction fragment length polymorphism (RFLP) was demonstrated in (NZW/NZB) F1 mice. However, little is known about the significance of TNF production in association with TNF gene polymorphism in human SLE. This study was designed to evaluate...
Topics
- Alleles
- Asian People
- Female
- Gene Expression
- Genetic Markers
- Homozygote
- Humans
- Korea
- Lupus Nephritis
- Lymphotoxin-alpha
- Male
- Polymorphism, Restriction Fragment Length
