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Analysis of the (CAG)n repeat at the IT15 locus in a population from Calabria (southern Italy).

Human biology - 1 Oct 1997

Leone O, Muglia M, Gabriele A L, Annesi G, Conforti F L, Imbrogno E, Imbrogno L, Brancati C

Abstract excerpt

The defect causing Huntington's disease (HD) has recently been discovered as an expanded CAG trinucleotide repeat located at the 5' end of the IT15 gene. This discovery allows the molecular diagnosis of HD by measuring the CAG repeat length. The normal and pathological repeat ranges in a population need to be established before a diagnostic test for HD can be performed. To determine the distribution of IT15...

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PMID: 9299885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Analysis of the (CAG)n repeat at the IT15 locus in a population from Calabria (southern Italy).PMID 9299885Read ↗

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