Article
Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons.
Biochemical and biophysical research communications - 18 Sept 1997
Hu X, Xia H, Srivastava S K, Herzog C, Awasthi Y C, Ji X, Zimniak P, Singh S V
Abstract excerpt
Allelic forms of hGSTP1-1 which differ from each other by their catalytic properties and, structurally, by the amino acid(s) in position(s) 104 or (and) 113 are known to exist in human populations. The four possible isoforms of hGSTP1-1 with isoleucine or valine in position 104 and with alanine or valine in position 113 were produced by site-directed mutagenesis of the cDNA followed by bacterial expression and...
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