Article
Allelic variation in the serotonin 5-HT2C receptor gene and migraine.
Neuroreport - 18 Aug 1997
Burnet P W, Harrison P J, Goodwin G M, Battersby S, Ogilvie A D, Olesen J, Russell M B
Abstract excerpt
The 5-HT2C (serotonin-2C) receptor has been implicated along with other components of the 5-HT system in the pathophysiology and pharmacotherapy of migraine. To investigate whether the 5-HT2C receptor gene contributes to the risk of migraine we performed an association study of allelic variation at codon 23 (Cys or Ser) of the gene in 242 migraineurs, including 73 with aura, and 129 controls. No differences nor...
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