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Article

The human complement regulatory factor-H-like protein 1, which represents a truncated form of factor H, displays cell-attachment activity

1 Sept 1997

Abstract excerpt

Complement factor H (FH) and factor-H-like protein 1 (FHL-1) are human plasma proteins with regulatory functions in the alternative pathway of complement activation. FH and FHL-1 are organized in repetitive elements termed short consensus repeats (SCRs) and the seven SCRs of FHL-1 are identical with the N-terminal domain of the 20 SCRs of FH. The fourth SCR of both proteins (SCR 4) includes the sequence...

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PMID: 9291099
DOI: 10.1042/bj3260321

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