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Bordetella pertussis binds the human complement regulator C4BP: role of filamentous hemagglutinin

1 Sept 1997

Abstract excerpt

C4BP (C4b-binding protein) is a high-molecular-weight plasma protein that inhibits the classical pathway of complement activation. Recent experiments have demonstrated that C4BP binds to many strains of the gram-positive bacterium Streptococcus pyogenes, a major respiratory tract pathogen. Binding to S. pyogenes was shown to be due to members of the M protein family, a group of surface proteins important for...

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PMID: 9284130
DOI: 10.1128/iai.65.9.3638-3643.1997

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Bordetella pertussis binds the human complement regulator C4BP: role of filamentous hemagglutininPMID 9284130Read ↗

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