Article
Novel SLA class I alleles of Chinese pig strains and their significance in xenotransplantation.
Cell research - 1 Aug 2003
Chen Fu Xiang, Tang Jun, Li Ning Li, Shen Bo Hua, Zhou Yun, Xie Jin, Chou Kuang Yen
Abstract excerpt
To lay background for studying rejection mechanisms in xenotransplantation and developing the strategies for intervention, class I genes of swine leukocyte antigens (SLA) of three Chinese pig strains Bm, Gz and Yn were cloned and sequenced. The cDNA of the class I loci P1 and P14 were amplified by RT-PCR and subjected to insert into sequencing vectors. All six allelic sequences we examined, each two for one...
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