Article
Characterization of swine leucocyte antigen alleles in a crossbred pig to be used in xenotransplant studies.
Tissue antigens - 1 Nov 2014
Reyes L M, Blosser R J, Smith R F, Miner A C, Paris L L, Blankenship R L, Tector M F, Tector A J
Abstract excerpt
We have characterized swine leucocyte antigen (SLA) classes I and II molecules of a domestic pig as a model for use in our xenotransplant program. Molecular characterization of the SLA classes I and II genes is critical to understanding the adaptive immune responses between swine and humans in the event of xenotransplantation. Seven swine leucocyte antigen genes (SLA-1, SLA-2, SLA-3, DQB1, DRB1, DQA and DRA) were...
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