Article
[Susceptibility to lung cancer in Chinese is associated with genetic polymorphism in cytochrome P4502E1].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jan 2000
Li Z, Tan W, Shao K
Abstract excerpt
OBJECTIVE: To investigate the genetic polymorphism of cytochrome P4502E1 (CYP2E1) as a susceptibility factor for lung cancer in Chinese population. METHODS: The genotype frequencies of RsaI restriction fragment length polymorphisms were analyzed in 92 lung cancer cases and 137 frequency-matched normal controls. RESULTS: The CYP2E1 c1/c1 genotype was found in 72.8% of lung cancer cases, which was significantly...
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