Article
[Cytochrome P450IA1 and the genetic susceptibility to esophageal carcinoma].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Mar 2000
Zhang H, Sun C, Li L, Yan M
Abstract excerpt
OBJECTIVES: To explore the susceptibility to esophageal carcinoma (EC) in different population with different cytochrome P450 IA1 (CYPIA1) genotype, and study the synergistic effects between CYPIA1 and smoking. METHODS: A case-control study (case = 111, control = 114) was used to compare the frequency of CYPIA1 genotype between EC and controls with a PCR method. RESULTS: The distribution of three genotypes of...
Topics
- Aged
- Case-Control Studies
- Cytochrome P-450 CYP1A1
- Esophageal Neoplasms
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Mutation
- Smoking
