Article
Peripheral blood microchimerism in human liver and renal transplant recipients: rejection despite donor-specific chimerism.
Transplantation - 15 Aug 1997
Sivasai K S, Alevy Y G, Duffy B F, Brennan D C, Singer G G, Shenoy S, Lowell J A, Howard T, Mohanakumar T
Abstract excerpt
BACKGROUND: Development of donor-specific microchimerism (DSM) has been proposed as one of the possible mechanisms for induction and maintenance of allograft tolerance. The aim of this study was to determine: (1) the state of DSM in liver transplant (LTx) and renal transplant (RTx) recipients, (2) whether the persistent presence of an allograft is a requirement for maintenance of chimerism, and (3) whether...
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