Article
Acute graft versus host disease after liver transplantation: patterns of lymphocyte chimerism.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Dec 2005
Domiati-Saad R, Klintmalm G B, Netto G, Agura E D, Chinnakotla S, Smith D M
Abstract excerpt
The diagnosis of acute graft versus host disease (aGVHD) following liver transplantation can be difficult, since many of the clinical signs can be caused by drug reactions or viral infections. To establish criteria for the persistence of donor T-cells versus engraftment, we measured donor T-cells by short tandem repeat (STR) assays in 49 liver transplant patients for 8 or more weeks post-transplant. Donor CD3+...
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