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Article

Amylenes do not lead to bacterial mutagenicity in contrast to structurally related epoxides.

BioMed research international - 1 Jan 2014

Westphal Götz A, Tüshaus Carolin, Monsé Christian, Rosenkranz Nina, Brüning Thomas, Bünger Jürgen

Abstract excerpt

Amylenes are unsaturated hydrocarbons (C5H10), such as 1-pentene, 2-pentene, 2-methyl-but-1-en (3-methyl-1-butene), 2-methyl-but-2-en (isopentene), and 3-methyl-but-1-en. We investigated bacterial mutagenicity of 1-pentene, 2-pentene, and 3-methyl-but-1-en in the Ames test. 2-Pentene was investigated as racemate and as pure diastereomers. We included the methyltransferase deficient Salmonella Typhimurium strain...

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Identifiers

PMID: 24511538
DOI: 10.1155/2014/592434
PMCID: PMC3912823

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