Article
Mutagenicity of benzo[a]pyrene and dibenzopyrenes in the Salmonella typhimurium TM677 and the MCL-5 human cell forward mutation assays.
Mutation research - 1 Mar 1995
Busby W F, Smith H, Crespi C L, Penman B W
Abstract excerpt
The mutagenicity of benzo[a]pyrene (B[a]P), dibenzo[ae]pyrene (DB[ae]P), dibenzo[ah]pyrene (DB[ah]P), dibenzo[ai]pyrene (DB[ai]P), and dibenzo[al]pyrene (DB[al]P) was measured in quantitative forward mutation assays with bacteria (Salmonella typhimurium TM677) and a metabolically competent cell line derived from human B-lymphoblastoid cells (MCL-5) that contained activity for five cytochrome P450s and microsomal...
Topics
- Benzo(a)pyrene
- Benzopyrenes
- Cell Line
- Humans
- Mutagenicity Tests
- Mutation
- Salmonella typhimurium
