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Article

Patterns of Hyaluronan Staining Are Modified by Fixation Techniques

1 Aug 1997

Abstract excerpt

The apparent intensity of hyaluronan (HA) staining in tissue sections can vary as a function of fixation techniques. We examined the histochemical distribution of HA in normal human skin using an HA-specific binding peptide derived from bovine nasal cartilage. The HA, particularly in the dermis, was best preserved in sections fixed in 10% acid-formalin with 70% ethanol. In contrast, sections fixed in the routine...

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PMID: 9267476
DOI: 10.1177/002215549704500813

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