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Article

Renal proximal tubule function is preserved in Cftr(tm2cam) deltaF508 cystic fibrosis mice.

The Journal of physiology - 15 Apr 2001

Kibble J D, Balloch K J, Neal A M, Hill C, White S, Robson L, Green R, Taylor C J

Abstract excerpt

1. Changes in proximal tubule function have been reported in cystic fibrosis patients. The aim of this study was to investigate proximal tubule function in the Cftr(tm2cam)deltaF508 cystic fibrosis (CF) mouse model. A range of techniques were used including renal clearance studies, in situ microperfusion, RT-PCR and whole-cell patch clamping. 2. Renal Na(+) clearance was similar in wild-type (1.4 +/- 0.3 microl...

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Share to Cystic Fibrosis
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 11306663
DOI: 10.1111/j.1469-7793.2001.0449f.x
PMCID: PMC2278541

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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