Article
Differences in Transcriptional Activity of Human Papillomavirus Type 6 Molecular Variants in Recurrent Respiratory Papillomatosis.
PloS one - 1 Jan 2015
Measso do Bonfim Caroline, Simão Sobrinho João, Lacerda Nogueira Rodrigo, Salgado Kupper Daniel, Cardoso Pereira Valera Fabiana, Lacerda Nogueira Maurício, Villa Luisa Lina, Rahal Paula, Sichero Laura
Abstract excerpt
A significant proportion of recurrent respiratory papillomatosis (RRP) is caused by human papillomavirus type 6 (HPV-6). The long control region (LCR) contains cis-elements for regulation of transcription. Our aim was to characterize LCR HPV-6 variants in RRP cases, compare promoter activity of these isolates and search for cellular transcription factors (TFs) that could explain the differences observed. The...
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