Placental trophoblasts resist infection by multiple human immunodeficiency virus (HIV) type 1 variants even with cytomegalovirus coinfection but support HIV replication after provirus transfection.

doi:10.1128/JVI.71.9.6359-6372.1997

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Article

Placental trophoblasts resist infection by multiple human immunodeficiency virus (HIV) type 1 variants even with cytomegalovirus coinfection but support HIV replication after provirus transfection.

Journal of virology - 1 Sept 1997

Kilani R T, Chang L J, Garcia-Lloret M I, Hemmings D, Winkler-Lowen B, Guilbert L J

Abstract excerpt

Whether cell-free human immunodeficiency virus type 1 (HIV-1) can productively infect placental trophoblasts (which in turn could transmit the virus into the fetal circulation) is controversial but essential to know for the evaluation of alternative routes (such as cell-mediated infection or trop...

Topics

Cell Membrane
Cells, Cultured
Coculture Techniques
Cytomegalovirus
Cytoplasm
DNA, Viral
Genetic Variation
HIV-1
HeLa Cells
Humans
Infant
Macrophages

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proviruses

Recombination, Genetic

T-Lymphocytes

Transfection

Trophoblasts

Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 9261353
DOI: 10.1128/JVI.71.9.6359-6372.1997
PMCID: PMC191909

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9261353-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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