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Article

Genetic analysis reveals ongoing HIV type 1 evolution in infected human placental trophoblast.

AIDS research and human retroviruses - 10 Dec 1999

Zachar V, Zacharova V, Fink T, Thomas R A, King B R, Ebbesen P, Jones T B, Goustin A S

Abstract excerpt

To provide a better understanding of the role of placenta in vertical human immunodeficiency virus (HIV) transmission, we have studied the infection of placental trophoblast in a group of 15 mother-neonate pairs. By nested PCR amplification of the C2V3 env gene region, HIV-1 has been found to infect the placenta in five cases (33%). Phylogenetic analysis of the cloned sequences showed that all recovered maternal...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10606090
DOI: 10.1089/088922299309711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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