Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD4-positive lymphoid cells rescue HIV-1 replication from abortively infected human primary endothelial cells.

Archives of virology - 1 Jan 1993

Scheglovitova O, Capobianchi M R, Antonelli G, Guanmu D, Dianzani F

Abstract excerpt

Human primary endothelial cell cultures, derived from umbilical vein (HUVEC), can be infected by different strains of HIV-1, but mature virus production remains undetectable both in supernatants and in cellular extracts. Yet viral DNA is transiently detectable during the first days of infection, but progressively declines during the subsequent days. This finding is characteristic of abortive infections....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to CD4 Antigens
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cells, Cultured

Share to Endothelium, Vascular

Share to Genetic Variation

Share to Virus Replication

Source

Identifiers

PMID: 7691046
DOI: 10.1007/BF01309538

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD4-positive lymphoid cells rescue HIV-1 replication from abortively infected human primary endothelial cells.PMID 7691046Read ↗

Replication of Marburg virus in human endothelial cells. A possible mechanism for the development of viral hemorrhagic disease.Semantic proximity Read ↗

Endothelial progenitor cell trafficking in human immunodeficiency virus-infected personsSemantic proximity Read ↗

Cytomegalovirus Impairs Cytotrophoblast-Induced Lymphangiogenesis and Vascular Remodeling in an in Vivo Human Placentation ModelSemantic proximity Read ↗

Placental trophoblasts resist infection by multiple human immunodeficiency virus (HIV) type 1 variants even with cytomegalovirus coinfection but support HIV replication after provirus transfection.Semantic proximity Read ↗

CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nef.Semantic proximity Read ↗

Adherence of human immunodeficiency virus-infected lymphocytes to fetal placental cells: a model of maternal --> fetal transmission.Semantic proximity Read ↗

Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycleSemantic proximity Read ↗

Leukemia inhibitory factor inhibits HIV-1 replication and is upregulated in placentae from nontransmitting womenSemantic proximity Read ↗

Maternal HIV type 1 infection suppresses MMP-1 expression in endothelial cells of uninfected newborns: nonviral vertical transmission of HIV type 1-related effects.Semantic proximity Read ↗

Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism.Semantic proximity Read ↗

Human immunodeficiency virus type-1 (HIV-1) infection of endothelial cells in vitro: a virological, ultrastructural and immuno-cytochemical approach.Semantic proximity Read ↗

Replication of different clones of human immunodeficiency virus type 1 in primary fetal human astroyctes: enhancement of viral gene expression by NefSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.