Article
Mutations that render the promoter of the histidine operon of Salmonella typhimurium insensitive to nutrient-rich medium repression and amino acid downshift.
Journal of bacteriology - 1 Aug 1997
Da Costa X J, Artz S W
Abstract excerpt
The effects of mutations in the promoter of the histidine operon of Salmonella typhimurium were examined in vivo. The wild-type chromosomal copy of the his promoter was replaced with mutations in the -10 hexamer sequence and in the region between the -10 hexamer and the transcriptional start poin...
Topics
- Amino Acids
- Culture Media
- Gene Expression Regulation, Bacterial
- Guanosine Tetraphosphate
- Histidine
- Mutagenesis, Site-Directed
- Mutation
- Operon
- Promoter Regions, Genetic
- Salmonella typhimurium
- Serine
