Role of mga in growth phase regulation of virulence genes of the group A streptococcus

doi:10.1128/jb.179.16.5178-5187.1997

Article

Role of mga in growth phase regulation of virulence genes of the group A streptococcus

1 Aug 1997

Abstract excerpt

To determine whether growth phase affects the expression of mga and other virulence-associated genes in the group A streptococcus (GAS), total RNA was isolated from the serotype M6 GAS strain JRS4 at different phases of growth and transcript levels were quantitated by hybridization with radiolabeled DNA probes. Expression of mga (which encodes a multiple gene regulator) and the Mga-regulated genes emm (which...

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