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Cloning and Characterization of Two Human Polyspecific Organic Cation Transporters

1 Jul 1997

Abstract excerpt

Previously we cloned a polyspecific transporter from rat (rOCT1) that is expressed in renal proximal tubules and hepatocytes and mediates electrogenic uptake of organic cations with different molecular structures. Recently a homologous transporter from rat kidney (rOCT2) was cloned but not characterized in detail. We report cloning and characterization of two homologous transporters from man (hOCT1 and hOCT2)...

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PMID: 9260930
DOI: 10.1089/dna.1997.16.871

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