Article
Somatic deletion of the imprinted 11p15 region in sporadic persistent hyperinsulinemic hypoglycemia of infancy is specific of focal adenomatous hyperplasia and endorses partial pancreatectomy.
The Journal of clinical investigation - 15 Aug 1997
de Lonlay P, Fournet J C, Rahier J, Gross-Morand M S, Poggi-Travert F, Foussier V, Bonnefont J P, Brusset M C, Brunelle F, Robert J J, Nihoul-Fékété C, Saudubray J M, Junien C
Abstract excerpt
Sporadic persistent hyperinsulinemic hypoglycemia of infancy (PHHI) or nesidioblastosis is a heterogeneous disorder characterized by profound hypoglycemia due to inappropriate hypersecretion of insulin. An important diagnostic goal is to distinguish patients with a focal hyperplasia of islet cells of the pancreas (FoPHHI) from those with a diffuse abnormality of islets (DiPHHI) because management strategies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.