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Article

Human chondrocyte expression of growth‐arrest‐specific gene 6 and the tyrosine kinase receptor axl. Potential role in autocrine signaling in cartilage

1 Aug 1997

Abstract excerpt

OBJECTIVE: To determine if human articular chondrocytes express the axl tyrosine kinase receptor and its ligand Gas-6, a protein product of growth-arrest-specific gene 6, and to determine if Gas-6 and axl function in the regulation of chondrocyte growth and survival. METHODS: The presence of Gas-6 and axl was examined in situ in human articular cartilage by immunohistochemistry and in vitro in cell culture...

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PMID: 9259426
DOI: 10.1002/art.1780400814

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