Article
No association or linkage between the 5-HT2a/T102C polymorphism and schizophrenia in Irish families.
American journal of medical genetics - 25 Jul 1997
Hawi Z, Myakishev M V, Straub R E, O'Neill A, Kendler K S, Walsh D, Gill M
Abstract excerpt
Recent findings of an association between schizophrenia and a T102C polymorphism at the 5-HT2a receptor gene (particularly with genotype 1-2 and 2-2 and allele 2) prompted us to investigate this marker in familial Irish schizophrenic patients, their relatives, and ethnically matched unrelated controls; 247 probands and 249 controls were included in this study. In contrast to some studies, we found no evidence of...
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