Article
No association or linkage between the 5-HT2a/T102C polymorphism and schizophrenia in Irish families.
American journal of medical genetics - 25 Jul 1997
Hawi Z, Myakishev M V, Straub R E, O'Neill A, Kendler K S, Walsh D, Gill M
Abstract excerpt
Recent findings of an association between schizophrenia and a T102C polymorphism at the 5-HT2a receptor gene (particularly with genotype 1-2 and 2-2 and allele 2) prompted us to investigate this marker in familial Irish schizophrenic patients, their relatives, and ethnically matched unrelated con...
Topics
- Disease Susceptibility
- Female
- Genotype
- Humans
- Ireland
- Linkage Disequilibrium
- Lod Score
- Male
- Models, Genetic
- Polymorphism, Genetic
- Receptor, Serotonin, 5-HT2A
- Receptors, Serotonin
- Schizophrenia
