Article
FISH analysis of translocations involving the short arm of chromosome 9 in lymphoid malignancies.
Genes, chromosomes & cancer - 1 Aug 1997
Leblanc T, Derré J, Flexor M, Le Coniat M, Leroux D, Rimokh R, Larsen C J, Berger R
Abstract excerpt
Deletion of the short arm of chromosome 9 (9p), resulting in the loss of the p16INK4a/MTS1 gene, now called CDKN2, has been found to occur frequently in acute lymphoblastic leukemia, even in the absence of a microscopically visible deletion. In this study, we have used YAC probes encompassing the CDKN2 locus to analyze by fluorescence in situ hybridization patients with leukemia and lymphoma and translocations...
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