FISH analysis of translocations involving the short arm of chromosome 9 in lymphoid malignancies.

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Article

FISH analysis of translocations involving the short arm of chromosome 9 in lymphoid malignancies.

Genes, chromosomes & cancer - 1 Aug 1997

Leblanc T, Derré J, Flexor M, Le Coniat M, Leroux D, Rimokh R, Larsen C J, Berger R

Abstract excerpt

Deletion of the short arm of chromosome 9 (9p), resulting in the loss of the p16INK4a/MTS1 gene, now called CDKN2, has been found to occur frequently in acute lymphoblastic leukemia, even in the absence of a microscopically visible deletion. In this study, we have used YAC probes encompassing the...

Topics

Adult
Aged
Alleles
Blotting, Southern
Carrier Proteins
Child
Chromosomes, Artificial, Yeast
Chromosomes, Human, Pair 9
Cyclin-Dependent Kinase Inhibitor p16
DNA Probes
DNA, Neoplasm
Female
Genes, Tumor Suppressor
Humans
In Situ Hybridization, Fluorescence
Karyotyping
Lymphoma
Male

Source

Open in PubMed

Identifiers

PMID: 9258663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9258663-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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