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Breakpoint characterization of der(9) deletions in chronic myeloid leukemia patients

23 Jul 2002

Abstract excerpt

Deletions adjacent to the 9/22 translocation breakpoint on the derivative chromosome 9 have recently been described in a substantial number of chronic myeloid leukemia (CML) cases, but their extension has not been characterized in detail. Using FISH with an appropriate set of BAC/PAC probes, we have characterized the deletion in 10 CML cases, identified by screening 71 patients at diagnosis. Five patients showed...

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PMID: 12353269
DOI: 10.1002/gcc.10116

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