Article
Derepressed utilization of L-malic acid and succinic acid by mutants of Pachysolen tannophilus.
Journal of industrial microbiology & biotechnology - 1 Jun 1997
Harrod C J, Rodriguez S B, Thornton R J
Abstract excerpt
Utilization of the tricarboxylic acid (TCA) cycle intermediates, L-malic acid and succinic acid, by the yeast Pachysolen tannophilus is repressed in the presence of glucose. Strains of P. tannophilus containing mutations in two hexokinases and a glucokinase were characterized for growth on glucose plus L-malic acid or succinic acid. Increased specific utilization rates of malic acid and succinic acid in the...
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