Allele loss in colorectal cancer at the Cowden disease/juvenile polyposis locus on 10q.

doi:10.1016/s0165-4608(97)00011-3

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Article

Allele loss in colorectal cancer at the Cowden disease/juvenile polyposis locus on 10q.

Cancer genetics and cytogenetics - 1 Aug 1997

Frayling I M, Bodmer W F, Tomlinson I P

Abstract excerpt

The genes that are mutated in inherited cancer syndromes are often involved in the pathogenesis of sporadic cancers of the types that characterize those syndromes. In colorectal cancer such loci include the familial adenomatous polyposis (APC) gene and the hereditary nonpolyposis colorectal cance...

Topics

Adenomatous Polyposis Coli
Alleles
Chromosomes, Human, Pair 10
Colorectal Neoplasms
Female
Gene Deletion
Hamartoma Syndrome, Multiple
Humans
Male

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