Article
Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF
5 Aug 1997
Abstract excerpt
The human androgen receptor (AR) is a ligand-activated transcription factor that regulates genes important for male sexual differentiation and development. To better understand the role of the receptor as a transcription factor we have studied the mechanism of action of the N-terminal transactivation function. In a protein-protein interaction assay the AR N terminus (amino acids 142-485) selectively bound to the...
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