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Article

Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours.

Oncogene - 17 Jul 1997

Vorechovský I, Tingby O, Hartman M, Strömberg B, Nister M, Collins V P, Toftgård R

Abstract excerpt

The naevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder characterized by multiple developmental defects and cancer susceptibility, in particular to basal cell carcinomas (BCCs). Medulloblastomas, primitive neuroectodermal tumours (PNETs) arising in childhood, occur in about 3-5% of NBCCS patients and a subset of PNETs was previously found with allelic imbalance at 9q22-q23, the region...

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Identifiers

PMID: 9233770
DOI: 10.1038/sj.onc.1201340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours.PMID 9233770Read ↗

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