Article
Crohn's disease and ulcerative colitis are associated with the DNA repair gene MLH1.
Annals of surgery - 1 Jun 1997
Pokorny R M, Hofmeister A, Galandiuk S, Dietz A B, Cohen N D, Neibergs H L
Abstract excerpt
OBJECTIVE: The purpose of this study was to determine whether there is an association between Crohn's disease and ulcerative colitis with MLH1. SUMMARY BACKGROUND DATA: Identification of genes involved in the etiology of inflammatory bowel disease may lead to the development of markers that objectively can define disease and permit therapy. The treatment of Crohn's disease of the colon and ulcerative colitis also...
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