Article
Transcription factors contributing to the pancreatic beta-cell phenotype.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Jun 1997
Madsen O D, Jensen J, Petersen H V, Pedersen E E, Oster A, Andersen F G, Jørgensen M C, Jensen P B, Larsson L I, Serup P
Abstract excerpt
Insulin promoter factor-1 (IPF1) (renamed to pancreatic-duodenal homeobox factor-1, PDX1) was originally cloned and characterized as an islet beta-cell specific insulin gene transcription factor (1) and later shown to be essential for the formation of the mature pancreas (2, 3). In the adult norm...
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