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Article

Detecting CFTR gene mutations by using primer oligo base extension and mass spectrometry.

Clinical chemistry - 1 Jul 1997

Braun A, Little D P, Köster H

Abstract excerpt

A new method for the reliable identification of localized variations in DNA by detection of associated diagnostic products with matrix-assisted laser desorption ionization time-of-flight mass spectrometry is described. The diagnostic products are generated by the primer oligo base extension (PROBE) reaction, which requires a single detection primer complementary to a region down-stream of a target strand's...

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Identifiers

PMID: 9216450

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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