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Article

Deoxycytidine kinase mRNA expression in childhood acute lymphoblastic leukemia.

Anti-cancer drugs - 1 Jun 1997

Stammler G, Zintl F, Sauerbrey A, Volm M

Abstract excerpt

Initial and relapsed childhood acute lymphoblastic leukemias (ALL) were investigated for mutations and expression of deoxycytidine kinase (dCK). dCK mediating toxicity of 1-beta-D-arabinofuranosylcytosine was analyzed semiquantitatively by RT-PCR and by single-strand conformation polymorphism. We found that patients with initial ALL experienced more frequently a relapse if dCK expression was low or absent. No...

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Identifiers

PMID: 9215616
DOI: 10.1097/00001813-199706000-00015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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