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Article

IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase.

The EMBO journal - 2 Jun 1997

Schouten G J, Vertegaal A C, Whiteside S T, Israël A, Toebes M, Dorsman J C, van der Eb A J, Zantema A

Abstract excerpt

The activity of transcription factor NFkappaB is regulated by its subcellular localization. In most cell types, NFkappaB is sequestered in the cytoplasm due to binding of the inhibitory protein IkappaB alpha. Stimulation of cells with a wide variety of agents results in degradation of IkappaB alp...

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Identifiers

PMID: 9214631
DOI: 10.1093/emboj/16.11.3133
PMCID: PMC1169932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9214631-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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