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Article

Neurexin-neuroligin transsynaptic interaction mediates learning-related synaptic remodeling and long-term facilitation in aplysia.

Neuron - 12 May 2011

Choi Yun-Beom, Li Hsiu-Ling, Kassabov Stefan R, Jin Iksung, Puthanveettil Sathyanarayanan V, Karl Kevin A, Lu Yang, Kim Joung-Hun, Bailey Craig H, Kandel Eric R

Abstract excerpt

Neurexin and neuroligin, which undergo heterophilic interactions with each other at the synapse, are mutated in some patients with autism spectrum disorder, a set of disorders characterized by deficits in social and emotional learning. We have explored the role of neurexin and neuroligin at sensory-to-motor neuron synapses of the gill-withdrawal reflex in Aplysia, which undergoes sensitization, a simple form of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21555073
DOI: 10.1016/j.neuron.2011.03.020
PMCID: PMC3136118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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