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Article

PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing.

Nucleic acids research - 15 Jul 1997

Nickerson D A, Tobe V O, Taylor S L

Abstract excerpt

Fluorescence-based sequencing is playing an increasingly important role in efforts to identify DNA polymorphisms and mutations of biological and medical interest. The application of this technology in generating the reference sequence of simple and complex genomes is also driving the development of new computer programs to automate base calling (Phred), sequence assembly (Phrap) and sequence assembly editing...

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Identifiers

PMID: 9207020
DOI: 10.1093/nar/25.14.2745
PMCID: PMC146817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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