Article
SNPdetector: a software tool for sensitive and accurate SNP detection.
PLoS computational biology - 1 Oct 2005
Zhang Jinghui, Wheeler David A, Yakub Imtiaz, Wei Sharon, Sood Raman, Rowe William, Liu Paul P, Gibbs Richard A, Buetow Kenneth H
Abstract excerpt
Identification of single nucleotide polymorphisms (SNPs) and mutations is important for the discovery of genetic predisposition to complex diseases. PCR resequencing is the method of choice for de novo SNP discovery. However, manual curation of putative SNPs has been a major bottleneck in the application of this method to high-throughput screening. Therefore it is critical to develop a more sensitive and accurate...
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