Article
Genes implicated in the pathogenesis of Alzheimer's disease.
Frontiers in bioscience : a journal and virtual library - 1 Jun 1997
Das H K, Lal H
Abstract excerpt
Both the early and late-onset Alzheimer's disease affect millions of people throughout the world. A number of molecules have been implicated in the pathogenesis of Alzheimer's disease. These include presenilin 1 and 2 (PS1 and PS2), a beta-amyloid peptide, and tau protein. Presenilin 1 and 2 genes implicated in the early-onset familial Alzheimer's disease have been cloned. Both PS1 and PS2 are integral membrane...
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