Article
Murine models of human genetic skeletal disorders.
Matrix biology : journal of the International Society for Matrix Biology - 1 May 1997
Li Y, Olsen B R
Abstract excerpt
Genetic and molecular biological studies have recently resulted in the identification of gene mutations responsible for a large number of human osteochondrodysplasias, skeletal disorders associated with abnormalities of cartilage and/or bone development and growth. Mouse strains carrying mutation...
Topics
- Animals
- Collagen
- Disease Models, Animal
- Dwarfism
- Humans
- Mice
- Mice, Mutant Strains
- Mutation
- Osteochondrodysplasias
- Proteoglycans