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Article

Molecular mechanisms regulating the myofilament response to Ca2+: implications of mutations causal for familial hypertrophic cardiomyopathy.

Basic research in cardiology - 1 Jan 1997

Palmiter K A, Solaro R J

Abstract excerpt

In this chapter we consider a current perception of the molecular mechanisms controlling myofilament activation with emphasis on alterations that may occur in familial hypertrophic cardiomyopathy (FHC). FHC is a sarcomeric disease (100) with an autosomal dominant pattern of heritability (27, 51)....

Topics

Actin Cytoskeleton
Animals
Calcium
Cardiomyopathy, Hypertrophic
Humans
Mutation
Myosins
Tropomyosin
Troponin
Troponin T

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9202846
DOI: 10.1007/BF00794070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9202846-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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