Article
Large majority of single-nucleotide mutations along the dystrophin gene can be explained by more than one mechanism of mutagenesis.
Human mutation - 1 Jan 1997
Todorova A, Danieli G A
Abstract excerpt
The present study reports for the first time on the analysis of the possible origin of single-base mutations along the highly mutable human dystrophin gene. Seventy-two mutations were considered and analyzed for consistency with the "slipped-mispairing" and "hypermutable CpG" models of mutagenesis. Moreover, repeated and symmetric elements, which could participate in the formation of secondary structures, were...
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